In many cases it is useful to test for differential abundance of sequences/taxa between two (or more) groups of microbiome samples. This is inherently a multiple comparisons/testing scenario, and so the same corrections for multiple testing that we learned in the previous section apply here. Many of the workflows will perform this correction by default.
The goal of this lab is to practice executing a few different workflows for differential abundance multiple testing (DESeq2, edgeR, metagenomeSeq), and combining their output into a single graphic (ggplot2, gridExtra).