12th Summer Institute in Statistics and Modeling in Infectious Diseases (SISMID)

Module 10: Infectious Diseases, Immunology and Within-Host Models

Mon Jul 20 to Wed Jul 22

Module dates/times: Monday, July 20; Tuesday, July 21, and Wednesday, July 22. Live sessions will start no earlier than 8 a.m. Pacific and end no later than 2:30 p.m. Pacific, except for Wednesdays. For modules that end on Wednesday, live sessions will end by 11 a.m. Pacific. For modules that start on Wednesday, live sessions will begin no earlier than 11:30 a.m.

Recommended but not required: Prior knowledge of R is helpful but not required.

This module provides an introduction to infectious diseases, the main components of the immune system, and mathematical modeling. Using pathogens such as HIV, TB, malaria, influenza and others, this module will introduce basic immunological concepts and explain how to use mathematical models to study aspects of within-host infection dynamics.

The focus will be on simple compartmental deterministic models. The use of those models to analyze the dynamics of pathogens, innate and adaptive immune responses and to design and evaluate intervention strategies, such as vaccines and drug treatments, are covered. Hands-on exercises using the programming language R will show how to construct and implement models.