SISCR 2017 Module 16 Survival Analysis in Clinical Trials

Module info

This module will cover more advanced topics in survival analysis, with an emphasis on applications in clinical trials. Knowledge of material in the Module 12: Introduction to Survival Analysis will be assumed.

  • Introduce methods suitable for examining the adjusted association between an explanatory variable and a censored event-data outcome.
  • Cover the important choice of the time scale for the analysis, and discuss how to make appropriate inferences when there are competing risks.
  • Cover time-dependent covariates and time-dependent stratification in a Cox regression model, including assumptions made by and effects of various covariate adjustment methods.

The course will focus on application and understanding the concepts; mathematical details will be kept to a minimum.