CR2508: Design and Analysis of Two-Phase Studies
New for 2025
Researchers often need to measure new variables, or validate existing measurements. Doing this for a whole cohort or database can be prohibitively expensive, so techniques are needed for choosing good subsamples and analyzing them efficiently. This module will give both a conceptual and practical introduction to planning and analyzing modern two-phase study designs. We will cover efficient weighted estimation using the whole cohort, and the optimal design and allocation of subsamples. Exercises will focus on practical aspects of implementing methods using the R survey package.

Thomas Lumley
Professor and Chair in Biostatistics
University of Auckland, New Zealand

Pamela Shaw
Senior Biostatistics Investigator
Kaiser Permanente Washington Health Research Institute